Teens who vape or smoke more likely to experience depression and anxiety, study of over 60,000 u.s. students finds. Youth using both e cigarettes and traditional tobacco report the highest levels of mental Vaping And Mental Health: Does Nicotine Use Cause Teen Depression? American Council on Science and Health Depression was more than twice as common among NYC teens ages 13 to 17 years who vaped than those who did not vape. Read our report to learn more about the mental Truth Initiative's "Depression Stick" Vaping Post